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Epistasis can lead to fragmented neutral spaces and contingency in evolution
In evolution, the effects of a single deleterious mutation can sometimes be compensated for by a second mutation which recovers the original phenotype. Such epistatic interactions have implications for the structure of genome space—namely, that networks of genomes encoding the same phenotype may not...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3297459/ https://ncbi.nlm.nih.gov/pubmed/22158953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2011.2183 |
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