Role of the BAHD1 Chromatin-Repressive Complex in Placental Development and Regulation of Steroid Metabolism

BAHD1 is a vertebrate protein that promotes heterochromatin formation and gene repression in association with several epigenetic regulators. However, its physiological roles remain unknown. Here, we demonstrate that ablation of the Bahd1 gene results in hypocholesterolemia, hypoglycemia and decrease...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Lakisic, Goran, Lebreton, Alice, Pourpre, Renaud, Wendling, Olivia, Libertini, Emanuele, Radford, Elizabeth J., Le Guillou, Morwenna, Champy, Marie-France, Wattenhofer-Donzé, Marie, Soubigou, Guillaume, Ait-Si-Ali, Slimane, Feunteun, Jean, Sorg, Tania, Coppée, Jean-Yves, Ferguson-Smith, Anne C., Cossart, Pascale, Bierne, Hélène
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777444/
https://ncbi.nlm.nih.gov/pubmed/26938916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005898
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