Overexpression of the Heterochromatinization Factor BAHD1 in HEK293 Cells Differentially Reshapes the DNA Methylome on Autosomes and X Chromosome

BAH domain-containing protein 1 (BAHD1) is involved in heterochromatin formation and gene repression in human cells. BAHD1 also localizes to the inactive X chromosome (Xi), but the functional significance of this targeting is unknown. So far, research on this protein has been hampered by its low end...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Libertini, Emanuele, Lebreton, Alice, Lakisic, Goran, Dillies, Marie-Agnès, Beck, Stephan, Coppée, Jean-Yves, Cossart, Pascale, Bierne, Hélène
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664705/
https://ncbi.nlm.nih.gov/pubmed/26648976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00339
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