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A Method for Label-Free, Differential Top-Down Proteomics

Biomarker discovery in the translational research has heavily relied on labeled and label-free quantitative bottom-up proteomics. Here, we describe a new approach to biomarker studies that utilizes high-throughput top-down proteomics and is the first to offer whole protein characterization and relat...

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Detalles Bibliográficos
Publicado en:Methods Mol Biol
Main Authors: Ntai, Ioanna, Toby, Timothy K., LeDuc, Richard D., Kelleher, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777307/
https://ncbi.nlm.nih.gov/pubmed/26867742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3524-6_8
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