New DNA methylation markers and global DNA hypomethylation are associated with oral cancer development

DNA promoter methylation of tumor suppressor genes and global DNA hypomethylation are common features of head and neck cancers. Our goal was to identify early DNA methylation changes in oral premalignant lesions (OPLs) that may serve as predictive markers of developing oral squamous cell carcinoma (...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Foy, Jean-Philippe, Pickering, Curtis R., Papadimitrakopoulou, Vassiliki, Jelinek, Jaroslav, Lin, Steven H., William, William N., Mitchell, Fredrick T., Wang, Jing, Lang, Wenhua, Feng, Lei, Zhang, Li, Kim, Edward S., Fan, You H., Hong, Waun K., El-Naggar, Adel K., Lee, J. Jack, Myers, Jeffrey N., Issa, Jean-Pierre, Lippman, Scott M., Mao, Li, Saintigny, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777304/
https://ncbi.nlm.nih.gov/pubmed/26342026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0179
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