New DNA methylation markers and global DNA hypomethylation are associated with oral cancer development

DNA promoter methylation of tumor suppressor genes and global DNA hypomethylation are common features of head and neck cancers. Our goal was to identify early DNA methylation changes in oral premalignant lesions (OPLs) that may serve as predictive markers of developing oral squamous cell carcinoma (...

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Pubblicato in:Cancer Prev Res (Phila)
Autori principali: Foy, Jean-Philippe, Pickering, Curtis R., Papadimitrakopoulou, Vassiliki, Jelinek, Jaroslav, Lin, Steven H., William, William N., Mitchell, Fredrick T., Wang, Jing, Lang, Wenhua, Feng, Lei, Zhang, Li, Kim, Edward S., Fan, You H., Hong, Waun K., El-Naggar, Adel K., Lee, J. Jack, Myers, Jeffrey N., Issa, Jean-Pierre, Lippman, Scott M., Mao, Li, Saintigny, Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777304/
https://ncbi.nlm.nih.gov/pubmed/26342026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0179
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