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Update on the management of Philadelphia chromosome positive chronic myelogenous leukemia: role of nilotinib

Chronic myelogenous leukemia (CML) is a pluripotent stem cell disease characterized by the presence of the Philadelphia chromosome and the bcr-abl gene. The discovery of tyrosine kinase inhibitors (TKIs) revolutionized therapy for CML, such that durable response, increased overall survival, and incr...

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Dettagli Bibliografici
Pubblicato in:Biologics
Autori principali: Emole, Josephine, Talabi, Taiwo, Pinilla-Ibarz, Javier
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777272/
https://ncbi.nlm.nih.gov/pubmed/27013862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S67844
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