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Bosutinib in the treatment of patients with Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia: an overview

Bosutinib is an orally bioavailable SRC/ABL tyrosine kinase inhibitor with activity against all phases of resistant chronic myeloid leukemia that do not express the T315I or V299L ABL kinase domain mutations. Bosutinib has a unique toxicity profile that is manageable. This paper provides an overview...

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Detalhes bibliográficos
Main Authors: Shen, Ann Q., Wilson, Nicole M., Gleason, Shannon L., Khoury, Hanna Jean
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891288/
https://ncbi.nlm.nih.gov/pubmed/24490020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620713510481
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