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Papaverine inhibits lipopolysaccharide-induced microglial activation by suppressing NF-κB signaling pathway
OBJECTIVE: To investigate the effects of papaverine (PAP) on lipopolysaccharide (LPS)-induced microglial activation and its possible mechanisms. MATERIALS AND METHODS: BV2 microglial cells were first pretreated with PAP (0, 0.4, 2, 10, and 50 μg/mL) and then received LPS stimulation. Transcription a...
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| Vydáno v: | Drug Des Devel Ther |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Dove Medical Press
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4777259/ https://ncbi.nlm.nih.gov/pubmed/27013863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S97380 |
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