Llwytho...

Flexible CDOCKER: Development and application of a pseudo-explicit structure-based docking method within CHARMM

Protein-ligand docking is a commonly used method for lead identification and refinement. While traditional structure-based docking methods represent the receptor as a rigid body, recent developments have been moving toward the inclusion of protein flexibility. Proteins exist in an inter-converting e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Comput Chem
Prif Awduron: Gagnon, Jessica K., Law, Sean M., Brooks, Charles L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776757/
https://ncbi.nlm.nih.gov/pubmed/26691274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.24259
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!