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Flexible CDOCKER: Development and application of a pseudo-explicit structure-based docking method within CHARMM

Protein-ligand docking is a commonly used method for lead identification and refinement. While traditional structure-based docking methods represent the receptor as a rigid body, recent developments have been moving toward the inclusion of protein flexibility. Proteins exist in an inter-converting e...

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Detalhes bibliográficos
Publicado no:J Comput Chem
Main Authors: Gagnon, Jessica K., Law, Sean M., Brooks, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776757/
https://ncbi.nlm.nih.gov/pubmed/26691274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.24259
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