Functional Effects of Schizophrenia-Linked Genetic Variants on Intrinsic Single-Neuron Excitability: A Modeling Study

BACKGROUND: Recent genome-wide association studies have identified a large number of genetic risk factors for schizophrenia (SCZ) featuring ion channels and calcium transporters. For some of these risk factors, independent prior investigations have examined the effects of genetic alterations on the...

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Gepubliceerd in:Biol Psychiatry Cogn Neurosci Neuroimaging
Hoofdauteurs: Mäki-Marttunen, Tuomo, Halnes, Geir, Devor, Anna, Witoelar, Aree, Bettella, Francesco, Djurovic, Srdjan, Wang, Yunpeng, Einevoll, Gaute T., Andreassen, Ole A., Dale, Anders M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776655/
https://ncbi.nlm.nih.gov/pubmed/26949748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpsc.2015.09.002
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