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Functional Effects of Schizophrenia-Linked Genetic Variants on Intrinsic Single-Neuron Excitability: A Modeling Study

BACKGROUND: Recent genome-wide association studies have identified a large number of genetic risk factors for schizophrenia (SCZ) featuring ion channels and calcium transporters. For some of these risk factors, independent prior investigations have examined the effects of genetic alterations on the...

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Detalles Bibliográficos
Publicado en:Biol Psychiatry Cogn Neurosci Neuroimaging
Main Authors: Mäki-Marttunen, Tuomo, Halnes, Geir, Devor, Anna, Witoelar, Aree, Bettella, Francesco, Djurovic, Srdjan, Wang, Yunpeng, Einevoll, Gaute T., Andreassen, Ole A., Dale, Anders M.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776655/
https://ncbi.nlm.nih.gov/pubmed/26949748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpsc.2015.09.002
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