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Structure–function analysis of myomaker domains required for myoblast fusion

During skeletal muscle development, myoblasts fuse to form multinucleated myofibers. Myomaker [Transmembrane protein 8c (TMEM8c)] is a muscle-specific protein that is essential for myoblast fusion and sufficient to promote fusion of fibroblasts with muscle cells; however, the structure and biochemic...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Millay, Douglas P., Gamage, Dilani G., Quinn, Malgorzata E., Min, Yi-Li, Mitani, Yasuyuki, Bassel-Duby, Rhonda, Olson, Eric N.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776501/
https://ncbi.nlm.nih.gov/pubmed/26858401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600101113
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