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High expression levels of macrophage migration inhibitory factor sustain the innate immune responses of neonates

The vulnerability to infection of newborns is associated with a limited ability to mount efficient immune responses. High concentrations of adenosine and prostaglandins in the fetal and neonatal circulation hamper the antimicrobial responses of newborn immune cells. However, the existence of mechani...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Roger, Thierry, Schneider, Anina, Weier, Manuela, Sweep, Fred C. G. J., Le Roy, Didier, Bernhagen, Jürgen, Calandra, Thierry, Giannoni, Eric
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776487/
https://ncbi.nlm.nih.gov/pubmed/26858459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1514018113
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