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Antibacterial activity and mechanism of action of auranofin against multi-drug resistant bacterial pathogens

Traditional methods employed to discover new antibiotics are both a time-consuming and financially-taxing venture. This has led researchers to mine existing libraries of clinical molecules in order to repurpose old drugs for new applications (as antimicrobials). Such an effort led to the discovery o...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Thangamani, Shankar, Mohammad, Haroon, Abushahba, Mostafa F. N., Sobreira, Tiago J. P., Hedrick, Victoria E., Paul, Lake N., Seleem, Mohamed N.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776257/
https://ncbi.nlm.nih.gov/pubmed/26936660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22571
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