Mapping Human Pluripotent-to-Cardiomyocyte Differentiation: Methylomes, Transcriptomes, and Exon DNA Methylation “Memories”

The directed differentiation of human cardiomyocytes (CMs) from pluripotent cells provides an invaluable model for understanding mechanisms of cell fate determination and offers considerable promise in cardiac regenerative medicine. Here, we utilize a human embryonic stem cell suspension bank, produ...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Tompkins, Joshua D., Jung, Marc, Chen, Chang-yi, Lin, Ziguang, Ye, Jingjing, Godatha, Swetha, Lizhar, Elizabeth, Wu, Xiwei, Hsu, David, Couture, Larry A., Riggs, Arthur D.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776252/
https://ncbi.nlm.nih.gov/pubmed/26981572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.01.021
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