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Mapping Human Pluripotent-to-Cardiomyocyte Differentiation: Methylomes, Transcriptomes, and Exon DNA Methylation “Memories”

The directed differentiation of human cardiomyocytes (CMs) from pluripotent cells provides an invaluable model for understanding mechanisms of cell fate determination and offers considerable promise in cardiac regenerative medicine. Here, we utilize a human embryonic stem cell suspension bank, produ...

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Bibliografske podrobnosti
izdano v:EBioMedicine
Main Authors: Tompkins, Joshua D., Jung, Marc, Chen, Chang-yi, Lin, Ziguang, Ye, Jingjing, Godatha, Swetha, Lizhar, Elizabeth, Wu, Xiwei, Hsu, David, Couture, Larry A., Riggs, Arthur D.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776252/
https://ncbi.nlm.nih.gov/pubmed/26981572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.01.021
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