Identification of Known and Novel Recurrent Viral Sequences in Data from Multiple Patients and Multiple Cancers

Virus discovery from high throughput sequencing data often follows a bottom-up approach where taxonomic annotation takes place prior to association to disease. Albeit effective in some cases, the approach fails to detect novel pathogens and remote variants not present in reference databases. We have...

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Publicado no:Viruses
Main Authors: Friis-Nielsen, Jens, Kjartansdóttir, Kristín Rós, Mollerup, Sarah, Asplund, Maria, Mourier, Tobias, Jensen, Randi Holm, Hansen, Thomas Arn, Rey-Iglesia, Alba, Richter, Stine Raith, Nielsen, Ida Broman, Alquezar-Planas, David E., Olsen, Pernille V. S., Vinner, Lasse, Fridholm, Helena, Nielsen, Lars Peter, Willerslev, Eske, Sicheritz-Pontén, Thomas, Lund, Ole, Hansen, Anders Johannes, Izarzugaza, Jose M. G., Brunak, Søren
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776208/
https://ncbi.nlm.nih.gov/pubmed/26907326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8020053
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