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4C-seq revealed long-range interactions of a functional enhancer at the 8q24 prostate cancer risk locus
Genome-wide association studies (GWAS) have identified >100 independent susceptibility loci for prostate cancer, including the hot spot at 8q24. However, how genetic variants at this locus confer disease risk hasn’t been fully characterized. Using circularized chromosome conformation capture (4C)...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4776156/ https://ncbi.nlm.nih.gov/pubmed/26934861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22462 |
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