Repeated Blockade of NMDA Receptors During Adolescence Impairs Reversal Learning and Disrupts GABAergic Interneurons in Rat Medial Prefrontal Cortex

Adolescence is of particular significance to schizophrenia, since psychosis onset typically occurs in this critical period. Based on the N-methyl-D-aspartate (NMDA) receptor hypofunction hypothesis of schizophrenia, in this study, we investigated whether and how repeated NMDA receptor blockade durin...

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Main Authors: Li, Ji-Tao, Su, Yun-Ai, Wang, Hong-Li, Zhao, Ying-Ying, Liao, Xue-Mei, Wang, Xiao-Dong, Si, Tian-Mei
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776083/
https://ncbi.nlm.nih.gov/pubmed/26973457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00017
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