Repeated Blockade of NMDA Receptors During Adolescence Impairs Reversal Learning and Disrupts GABAergic Interneurons in Rat Medial Prefrontal Cortex

Adolescence is of particular significance to schizophrenia, since psychosis onset typically occurs in this critical period. Based on the N-methyl-D-aspartate (NMDA) receptor hypofunction hypothesis of schizophrenia, in this study, we investigated whether and how repeated NMDA receptor blockade durin...

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Vydáno v:Front Mol Neurosci
Hlavní autoři: Li, Ji-Tao, Su, Yun-Ai, Wang, Hong-Li, Zhao, Ying-Ying, Liao, Xue-Mei, Wang, Xiao-Dong, Si, Tian-Mei
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776083/
https://ncbi.nlm.nih.gov/pubmed/26973457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00017
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