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Dynamics of the Ligand Binding Domain Layer during AMPA Receptor Activation
Ionotropic glutamate receptors are postsynaptic tetrameric ligand-gated channels whose activity mediates fast excitatory transmission. Glutamate binding to clamshell-shaped ligand binding domains (LBDs) triggers opening of the integral ion channel, but how the four LBDs orchestrate receptor activati...
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| Publicado en: | Biophys J |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4776031/ https://ncbi.nlm.nih.gov/pubmed/26910426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.12.033 |
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