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Mutational Analysis of Quinolone Resistance Protein QnrVC7 Provides Novel Insights into the Structure-Activity Relationship of Qnr Proteins

This study assessed the functional importance of residues located at the i(−2) position of face 4 of the tandem repeat loops of the quinolone resistance protein QnrVC7 through mutagenesis studies. The i(−2) position of face 4 on different coils required residues with different natures. Some substitu...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Po, Kathy Hiu Laam, Chan, Edward Wai Chi, Chen, Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775992/
https://ncbi.nlm.nih.gov/pubmed/26824937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01805-15
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