Defining Clinical Exposures of Cefepime for Gram-Negative Bloodstream Infections That Are Associated with Improved Survival

The percentage of time that free drug concentrations remain above the MIC (fT(>MIC)) that is necessary to prevent mortality among cefepime-treated patients with Gram-negative bloodstream infections (GNBSI) is poorly defined. We conducted a retrospective study of adult patients with GNBSI. Eligibl...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Rhodes, Nathaniel J., Kuti, Joseph L., Nicolau, David P., Van Wart, Scott, Nicasio, Anthony M., Liu, Jiajun, Lee, Benjamin J., Neely, Michael N., Scheetz, Marc H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Clinical Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775983/
https://ncbi.nlm.nih.gov/pubmed/26666929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01956-15
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