Mifepristone Suppresses Basal Triple-Negative Breast Cancer Stem Cells by Down-regulating KLF5 Expression

Triple-negative breast cancer (TNBC) is currently the most malignant subtype of breast cancers without effective targeted therapies. Mifepristone (MIF), a drug regularly used for abortion, has been reported to have anti-tumor activity in multiple hormone-dependent cancers, including luminal type bre...

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Bibliografiske detaljer
Udgivet i:Theranostics
Main Authors: Liu, Rong, Shi, Peiguo, Nie, Zhi, Liang, Huichun, Zhou, Zhongmei, Chen, Wenlin, Chen, Haijun, Dong, Chao, Yang, Runxiang, Liu, Suling, Chen, Ceshi
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775863/
https://ncbi.nlm.nih.gov/pubmed/26941846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.14315
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