Evaluation of a 3-hydroxypyridin-2-one (2,3-HOPO) Based Macrocyclic Chelator for (89)Zr(4+) and Its Use for ImmunoPET Imaging of HER2 Positive Model of Ovarian Carcinoma in Mice

A novel octadentate 3-hydroxypyridin-2-one (2,3-HOPO) based di-macrocyclic ligand was evaluated for chelation of (89)Zr; subsequently, it was used as a bi-functional chelator for preparation of (89)Zr-labeled antibodies. Quantitative chelation of (89)Zr(4+) with the octadentate ligand forming (89)Zr...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Theranostics
Hlavní autoři: N.Tinianow, Jeff, Pandya, Darpan N., Pailloux, Sylvie L., Ogasawara, Annie, Vanderbilt, Alexander N., Gill, Herman S., Williams, Simon-P., Wadas, Thaddeus J., Magda, Darren, Marik, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2016
Témata:
Short Research Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775861/
https://ncbi.nlm.nih.gov/pubmed/26941844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.14261
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky