Schisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathway

AIM: The nuclear factor erythroid 2-related factor 2 (NRF2) acts through the antioxidant response element (ARE) to regulate the expression of many detoxifying and antioxidant genes responsible for cytoprotective processes. We previously reported that Schisandrol B (SolB) isolated from Schisandra sph...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Jiang, Yi-ming, Wang, Ying, Tan, Hua-sen, Yu, Tao, Fan, Xiao-mei, Chen, Pan, Zeng, Hang, Huang, Min, Bi, Hui-chang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775844/
https://ncbi.nlm.nih.gov/pubmed/26806302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.120
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