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The nature of myeloid-derived suppressor cells in the tumor microenvironment

Myeloid-derived suppressor cells (MDSC) are one of the major components of the tumor microenvironment. The main feature of these cells is their potent immune suppressive activity. MDSC are generated in the bone marrow, and in tumor-bearing hosts, migrate to peripheral lymphoid organs and the tumor t...

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Détails bibliographiques
Publié dans:Trends Immunol
Auteurs principaux: Kumar, Vinit, Patel, Sima, Tcyganov, Evgenii, Gabrilovich, Dmitry I.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775398/
https://ncbi.nlm.nih.gov/pubmed/26858199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2016.01.004
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