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The nature of myeloid-derived suppressor cells in the tumor microenvironment

Myeloid-derived suppressor cells (MDSC) are one of the major components of the tumor microenvironment. The main feature of these cells is their potent immune suppressive activity. MDSC are generated in the bone marrow, and in tumor-bearing hosts, migrate to peripheral lymphoid organs and the tumor t...

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Dettagli Bibliografici
Pubblicato in:Trends Immunol
Autori principali: Kumar, Vinit, Patel, Sima, Tcyganov, Evgenii, Gabrilovich, Dmitry I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775398/
https://ncbi.nlm.nih.gov/pubmed/26858199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2016.01.004
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