EGFR signaling enhances aerobic glycolysis in triple negative breast cancer cells to promote tumor growth and immune escape

Oncogenic signaling reprograms cancer cell metabolism to augment the production of glycolytic metabolites in favor of tumor growth. The ability of cancer cells to evade immunosurveillance and the role of metabolic regulators in T cell functions suggest that oncogene-induced metabolic reprogramming m...

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Publicado en:Cancer Res
Main Authors: Lim, Seung-Oe, Li, Chia-Wei, Xia, Weiya, Lee, Heng-Huan, Chang, Shih-Shin, Shen, Jia, Hsu, Jennifer L., Raftery, Dan, Djukovic, Danijel, Gu, Haiwei, Chang, Wei-Chao, Wang, Hung-Ling, Chen, Mong-Liang, Huo, Longfei, Chen, Chung-Hsuan, Wu, Yun, Sahin, Aysegul, Hanash, Samir M., Hortobagyi, Gabriel N., Hung, Mien-Chie
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775355/
https://ncbi.nlm.nih.gov/pubmed/26759242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2478
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