Performance of Different Analytical Software Packages in Quantification of DNA Methylation by Pyrosequencing

BACKGROUND: Pyrosequencing has emerged as an alternative method of nucleic acid sequencing, well suited for many applications which aim to characterize single nucleotide polymorphisms, mutations, microbial types and CpG methylation in the target DNA. The commercially available pyrosequencing systems...

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Veröffentlicht in:PLoS One
Hauptverfasser: Grasso, Chiara, Trevisan, Morena, Fiano, Valentina, Tarallo, Valentina, De Marco, Laura, Sacerdote, Carlotta, Richiardi, Lorenzo, Merletti, Franco, Gillio-Tos, Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775062/
https://ncbi.nlm.nih.gov/pubmed/26934703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150483
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