Performance of Different Analytical Software Packages in Quantification of DNA Methylation by Pyrosequencing

BACKGROUND: Pyrosequencing has emerged as an alternative method of nucleic acid sequencing, well suited for many applications which aim to characterize single nucleotide polymorphisms, mutations, microbial types and CpG methylation in the target DNA. The commercially available pyrosequencing systems...

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Publicat a:PLoS One
Autors principals: Grasso, Chiara, Trevisan, Morena, Fiano, Valentina, Tarallo, Valentina, De Marco, Laura, Sacerdote, Carlotta, Richiardi, Lorenzo, Merletti, Franco, Gillio-Tos, Anna
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775062/
https://ncbi.nlm.nih.gov/pubmed/26934703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150483
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