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Mathematical Modelling of a Brain Tumour Initiation and Early Development: A Coupled Model of Glioblastoma Growth, Pre-Existing Vessel Co-Option, Angiogenesis and Blood Perfusion

We propose a coupled mathematical modelling system to investigate glioblastoma growth in response to dynamic changes in chemical and haemodynamic microenvironments caused by pre-existing vessel co-option, remodelling, collapse and angiogenesis. A typical tree-like architecture network with different...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Cai, Yan, Wu, Jie, Li, Zhiyong, Long, Quan
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774981/
https://ncbi.nlm.nih.gov/pubmed/26934465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150296
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