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Mathematical Modelling of a Brain Tumour Initiation and Early Development: A Coupled Model of Glioblastoma Growth, Pre-Existing Vessel Co-Option, Angiogenesis and Blood Perfusion

We propose a coupled mathematical modelling system to investigate glioblastoma growth in response to dynamic changes in chemical and haemodynamic microenvironments caused by pre-existing vessel co-option, remodelling, collapse and angiogenesis. A typical tree-like architecture network with different...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cai, Yan, Wu, Jie, Li, Zhiyong, Long, Quan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774981/
https://ncbi.nlm.nih.gov/pubmed/26934465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150296
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