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Room-Temperature Direct β-Arylation of Thiophenes and Benzo[b]thiophenes and Kinetic Evidence for a Heck-type Pathway

[Image: see text] The first example of a regioselective β-arylation of benzo[b]thiophenes and thiophenes at room temperature with aryl iodides as coupling partners is reported. This methodology stands out for its operational simplicity: no prefunctionalization of either starting material is required...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Colletto, Chiara, Islam, Saidul, Juliá-Hernández, Francisco, Larrosa, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774971/
https://ncbi.nlm.nih.gov/pubmed/26788885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b12242
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