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Reactivation of Latent HIV-1 Expression by Engineered TALE Transcription Factors
The presence of replication-competent HIV-1 –which resides mainly in resting CD4(+) T cells–is a major hurdle to its eradication. While pharmacological approaches have been useful for inducing the expression of this latent population of virus, they have been unable to purge HIV-1 from all its reserv...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4774903/ https://ncbi.nlm.nih.gov/pubmed/26933881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150037 |
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