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Structural investigation of the thymidine phosphorylase from Salmonella typhimurium in the unliganded state and its complexes with thymidine and uridine

Highly specific thymidine phosphorylases catalyze the phosphorolytic cleavage of thymidine, with the help of a phosphate ion, resulting in thymine and 2-deoxy-α-d-ribose 1-phosphate. Thymidine phosphorylases do not catalyze the phosphorolysis of uridine, in contrast to nonspecific pyrimidine nucleos...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Balaev, Vladislav V., Lashkov, Alexander A., Gabdulkhakov, Azat G., Dontsova, Maria V., Seregina, Tatiana A., Mironov, Alexander S., Betzel, Christian, Mikhailov, Al’bert M.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774882/
https://ncbi.nlm.nih.gov/pubmed/26919527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X1600162X
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