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Ectodermal Wnt Controls Nasal Pit Morphogenesis Through Modulation of the BMP/FGF/JNK Signaling Axis

BACKGROUND: Mutations of WNT3, WNT5A, WNT9B, and WNT11 genes are associated with orofacial birth defects, including non-syndromic cleft lip with cleft palate in humans. However, the source of Wnt ligands and their signaling effects on the orofacial morphogenetic process remain elusive. RESULTS: Usin...

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Bibliografski detalji
Izdano u:Dev Dyn
Glavni autori: Zhu, Xiao-Jing, Liu, Yudong, Yuan, Xueyan, Wang, Min, Zhao, Wanxin, Yang, Xueqin, Zhang, Xiaoyun, Hsu, Wei, Qiu, Mengsheng, Zhang, Ze, Zhang, Zunyi
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774528/
https://ncbi.nlm.nih.gov/pubmed/26661618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24376
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