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Curcumin suppresses transforming growth factor-β1-induced cardiac fibroblast differentiation via inhibition of Smad-2 and p38 MAPK signaling pathways
The differentiation of cardiac fibroblasts (CFs) into myofibroblasts and the subsequent deposition of the extracellular matrix is associated with myocardial fibrosis following various types of myocardial injury. In the present study, the effect of curcumin, which is a pharmacologically-safe natural...
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| Published in: | Exp Ther Med |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
D.A. Spandidos
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4774370/ https://ncbi.nlm.nih.gov/pubmed/26998027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.2969 |
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