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Curcumin suppresses transforming growth factor-β1-induced cardiac fibroblast differentiation via inhibition of Smad-2 and p38 MAPK signaling pathways

The differentiation of cardiac fibroblasts (CFs) into myofibroblasts and the subsequent deposition of the extracellular matrix is associated with myocardial fibrosis following various types of myocardial injury. In the present study, the effect of curcumin, which is a pharmacologically-safe natural...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: LIU, HUZI, LIU, AIJUN, SHI, CHUNLI, LI, BAO
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774370/
https://ncbi.nlm.nih.gov/pubmed/26998027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.2969
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