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Effects of tanshinone IIA on the transforming growth factor β1/Smad signaling pathway in rat cardiac fibroblasts

OBJECTIVES: This study explores the mechanism of tanshinone IIA (TSN)-mediated inhibition of myocardial fibrosis by investigating the effect of TSN on transforming growth factor β1 (TGFβ1) signal transduction in rat cardiac fibroblasts (CFs). MATERIALS AND METHODS: CFs were isolated from neonatal Sp...

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Vydáno v:Indian J Pharmacol
Hlavní autoři: Zhan, Cheng-Ye, Tang, Jin-Hui, Zhou, Dai-Xing, Li, Zhi-Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: Medknow Publications & Media Pvt Ltd 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264080/
https://ncbi.nlm.nih.gov/pubmed/25538336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0253-7613.144933
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