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Rho/Rock cross-talks with transforming growth factor-β/Smad pathway participates in lung fibroblast-myofibroblast differentiation

The differentiation of fibroblasts, which are promoted by transforming growth factor-β (TGF-β)/Smad, is involved in the process of pulmonary fibrosis. The Rho/Rho-associated coiled-coil-forming protein kinase (Rock) pathway may regulate the fibroblast differentiation and myofibroblast expression of...

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Dettagli Bibliografici
Autori principali: JI, HONG, TANG, HAIYING, LIN, HONGLI, MAO, JINGWEI, GAO, LILI, LIU, JIA, WU, TAIHUA
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179758/
https://ncbi.nlm.nih.gov/pubmed/25279146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2014.323
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