AB198. Estrogen attenuates the TGFβ1-induced conversion of primary penile tunica albuginea fibroblasts into myofibroblasts and inhibits collagen production and myofibroblast contraction by modulating the Smad and Rho/ROCK signaling pathways

OBJECTIVE: The transformation of penile tunica albuginea fibroblasts (TAFs) into myofibroblasts plays an important role in the pathological progress of Peyronie’s disease (PD). However, no treatment is currently available to address this issue. Estrogen has been shown to inhibit the progression of f...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Transl Androl Urol
Asıl Yazarlar: Jiang, Hesong, Dai, Yutian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: AME Publishing Company 2015
Konular:
Accepted Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4708689/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2223-4683.2015.s198
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