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IL-27 inhibits the TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells

BACKGROUND: IL-27 is a multifunctional cytokine that has both pro-inflammatory and anti-inflammatory functions. Although IL-27 has been shown to potently inhibit lung fibrosis, the detailed mechanism of IL-27 in this process is poorly understood. Epithelial–mesenchymal transition (EMT) is one of the...

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Publicat a:BMC Cell Biol
Autors principals: Dong, Zhaoxing, Tai, Wenlin, Lei, Wen, Wang, Yin, Li, ZhenKun, Zhang, Tao
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774182/
https://ncbi.nlm.nih.gov/pubmed/26932661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-016-0084-x
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