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HSA: integrating multi-track Hi-C data for genome-scale reconstruction of 3D chromatin structure

Genome-wide 3C technologies (Hi-C) are being increasingly employed to study three-dimensional (3D) genome conformations. Existing computational approaches are unable to integrate accumulating data to facilitate studying 3D chromatin structure and function. We present HSA (http://ouyanglab.jax.org/hs...

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Veröffentlicht in:Genome Biol
Hauptverfasser: Zou, Chenchen, Zhang, Yuping, Ouyang, Zhengqing
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774023/
https://ncbi.nlm.nih.gov/pubmed/26936376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0896-1
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