Channelopathy-related SCN10A gene variants predict cerebellar dysfunction in multiple sclerosis

OBJECTIVE: To determine the motor-behavioral and neural correlates of putative functional common variants in the sodium-channel Na(V)1.8 encoding gene (SCN10A) in vivo in patients with multiple sclerosis (MS). METHODS: We recruited 161 patients with relapsing-onset MS and 94 demographically comparab...

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Publicat a:Neurology
Autors principals: Roostaei, Tina, Sadaghiani, Shokufeh, Park, Min Tae M., Mashhadi, Rahil, Nazeri, Aria, Noshad, Sina, Salehi, Mohammad Javad, Naghibzadeh, Maryam, Moghadasi, Abdorreza Naser, Owji, Mahsa, Doosti, Rozita, Taheri, Amir Pejman Hashemi, Rad, Ali Shakouri, Azimi, Amirreza, Chakravarty, M. Mallar, Voineskos, Aristotle N., Nazeri, Arash, Sahraian, Mohammad Ali
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773947/
https://ncbi.nlm.nih.gov/pubmed/26740675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002326
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