Channelopathy-related SCN10A gene variants predict cerebellar dysfunction in multiple sclerosis

OBJECTIVE: To determine the motor-behavioral and neural correlates of putative functional common variants in the sodium-channel Na(V)1.8 encoding gene (SCN10A) in vivo in patients with multiple sclerosis (MS). METHODS: We recruited 161 patients with relapsing-onset MS and 94 demographically comparab...

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發表在:Neurology
Main Authors: Roostaei, Tina, Sadaghiani, Shokufeh, Park, Min Tae M., Mashhadi, Rahil, Nazeri, Aria, Noshad, Sina, Salehi, Mohammad Javad, Naghibzadeh, Maryam, Moghadasi, Abdorreza Naser, Owji, Mahsa, Doosti, Rozita, Taheri, Amir Pejman Hashemi, Rad, Ali Shakouri, Azimi, Amirreza, Chakravarty, M. Mallar, Voineskos, Aristotle N., Nazeri, Arash, Sahraian, Mohammad Ali
格式: Artigo
語言:Inglês
出版: Lippincott Williams & Wilkins 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773947/
https://ncbi.nlm.nih.gov/pubmed/26740675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002326
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