Na/K-ATPase signaling regulates collagen synthesis through microRNA-29b-3p in cardiac fibroblasts

Chronic kidney disease (CKD) is accompanied by cardiac fibrosis, hypertrophy, and dysfunction, which are commonly referred to as uremic cardiomyopathy. Our previous studies found that Na/K-ATPase ligands or 5/6th partial nephrectomy (PNx) induces cardiac fibrosis in rats and mice. The current study...

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Bibliographic Details
Published in:Physiol Genomics
Main Authors: Drummond, Christopher A., Hill, Michael C., Shi, Huilin, Fan, Xiaoming, Xie, Jeffrey X., Haller, Steven T., Kennedy, David J., Liu, Jiang, Garrett, Michael R., Xie, Zijian, Cooper, Christopher J., Shapiro, Joseph I., Tian, Jiang
Format: Artigo
Language:Inglês
Published: American Physiological Society 2015
Subjects:
Regulation of Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773889/
https://ncbi.nlm.nih.gov/pubmed/26702050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00116.2015
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