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Protein Carbonylation of an Amino Acid Residue of the Na/K‐ATPase α1 Subunit Determines Na/K‐ATPase Signaling and Sodium Transport in Renal Proximal Tubular Cells

BACKGROUND: We have demonstrated that cardiotonic steroids, such as ouabain, signaling through the Na/K‐ATPase, regulate sodium reabsorption in the renal proximal tubule. By direct carbonylation modification of the Pro222 residue in the actuator (A) domain of pig Na/K‐ATPase α1 subunit, reactive oxy...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Am Heart Assoc
मुख्य लेखकों: Yan, Yanling, Shapiro, Anna P., Mopidevi, Brahma R., Chaudhry, Muhammad A., Maxwell, Kyle, Haller, Steven T., Drummond, Christopher A., Kennedy, David J., Tian, Jiang, Malhotra, Deepak, Xie, Zi‐jian, Shapiro, Joseph I., Liu, Jiang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079028/
https://ncbi.nlm.nih.gov/pubmed/27613772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.003675
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