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Positioning of extracellular loop 1 affects pore gating of the cystic fibrosis transmembrane conductance regulator
The cystic fibrosis (CF) transmembrane conductance regulator (CFTR) is a chloride ion channel, the dysfunction of which directly leads to the life-shortening disease CF. Extracellular loop 1 (ECL1) of CFTR contains several residues involved in stabilizing the open state of the channel; some, includi...
Enregistré dans:
| Publié dans: | Am J Physiol Lung Cell Mol Physiol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4773844/ https://ncbi.nlm.nih.gov/pubmed/26684250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00259.2015 |
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