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Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI Inhibitors
The sonic hedgehog (Shh) signaling pathway is a major regulator of cell differentiation, cell proliferation, and tissue polarity. Aberrant activation of the Shh pathway has been shown in a variety of human cancers, including, basal cell carcinoma, malignant gliomas, medulloblastoma, leukemias, and c...
Gardado en:
| Publicado en: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4773745/ https://ncbi.nlm.nih.gov/pubmed/26891329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers8020022 |
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